Uphononongo lwakutsha nje luphonononge iziphumo zonyango lweoksijini ye-hyperbaric ekusebenzeni kwentliziyo yabantu abafumana i-COVID ende, ebhekisa kwimiba eyahlukeneyo yezempilo eqhubekayo okanye ephinda yenzeke emva kosulelo lwe-SARS-CoV-2.
Ezi ngxaki zinokubandakanya isingqi sentliziyo esingaqhelekanga kunye nomngcipheko owongeziweyo wokungasebenzi kakuhle kwentliziyo.Abaphandi bafumanise ukuba ukuphefumla ngoxinzelelo olukhulu, ioksijini esulungekileyo kunokunceda ekuphuculeni ukucutheka kwentliziyo kwizigulana ezinde ze-COVID.
Uphononongo lukhokelwa nguNjingalwazi uMarina Leitman osuka kwiSackler School of Medicine kwiYunivesithi yaseTel Aviv kunye neZiko lezoNyango laseShamir kwaSirayeli.Nangona iziphumo zivezwe kwinkomfa ngoMeyi 2023 ebanjwe yi-European Society of Cardiology, abangekaphononongwa ngabalingane.
I-COVID ende kunye neenkxalabo zentliziyo
I-COVID ende, ekwabizwa ngokuba yi-post-COVID syndrome, ichaphazela malunga ne-10-20% yabantu abaye bane-COVID-19.Ngelixa uninzi lwabantu luchacha ngokupheleleyo kwintsholongwane, i-COVID ende inokufunyaniswa xa iimpawu ziqhubeka ubuncinci iinyanga ezintathu emva kokuqala kweempawu ze-COVID-19.
Iimpawu ze-COVID ende ziquka imiba eyahlukeneyo yezempilo, kubandakanya ukuphefumla, ubunzima bokuqonda (okubhekiselwa kubo njengenkungu yengqondo), uxinzelelo, kunye neengxaki ezininzi zentliziyo.Abantu abane-COVID ende basemngciphekweni owonyukayo wokuba nesifo sentliziyo, ukusilela kwentliziyo, kunye nezinye iimeko ezinxulumene noko.
Nditsho nabantu abangenazo naziphi na iingxaki zentliziyo zangaphambili okanye umngcipheko omkhulu wesifo sentliziyo baye bafumana ezi mpawu, njengoko kubonisiwe luphononongo olwenziwe ngo-2022.
Iindlela zophononongo
UGqr. Leitman kunye namaqabane akhe baqesha abaguli abangama-60 ababeneempawu zexesha elide ze-COVID-19, kwanasemva kokuthomalalisa ukuya kwimeko ephakathi, ethatha iinyanga ezintathu ubuncinci.Eli qela laliquka abantu abasesibhedlele nabangalaliswanga esibhedlele.
Ukuqhuba isifundo sabo, abaphandi bahlula abathathi-nxaxheba ngamaqela amabini: enye ifumana i-hyperbaric oxygen therapy (HBOT) kwaye enye ifumana inkqubo yokulinganisa (sham).I-asayinimenti yenziwe ngokungacwangciswanga, ngenani elilinganayo lezifundo kwiqela ngalinye.Ebudeni beeveki ezisibhozo, mntu ngamnye wayeneeseshoni ezintlanu ngeveki.
Iqela le-HBOT lifumene i-100% oksijini kwixinzelelo lwe-2 atmospheres kwimizuzu ye-90, kunye nekhefu elifutshane rhoqo ngemizuzu ye-20.Ngakolunye uhlangothi, iqela le-sham lifumene i-21% oksijini kwixinzelelo lwe-1 emoyeni ngexesha elifanayo kodwa ngaphandle kokuphuka.
Ukongezelela, bonke abathathi-nxaxheba bafumana i-echocardiography, uvavanyo lokuvavanya umsebenzi wenhliziyo, ngaphambi kweseshoni yokuqala ye-HBOT kunye ne-1 kwiiveki ze-3 emva kweseshoni yokugqibela.
Ekuqaleni kophononongo, i-29 kubathathi-nxaxheba be-60 babenomlinganiselo we-global longitudinal strain (GLS) -17.8%.Phakathi kwabo, i-16 yabelwa kwiqela le-HBOT, ngelixa i-13 eseleyo yayikwiqela le-sham.
Iziphumo zophononongo
Emva kokufumana unyango, iqela lokungenelela lafumana ukwanda okuphawulekayo kwi-GLS eqhelekileyo, ukufikelela kwi-20.2%.Ngokufanayo, iqela le-sham nalo liye lanyuka kwi-avareji ye-GLS, eyafikelela -19.1%.Nangona kunjalo, kuphela umlinganiselo wangaphambili ubonise umehluko omkhulu xa kuthelekiswa nomlinganiselo wokuqala ekuqaleni kophononongo.
UGqr. Leitman wenze uqwalaselo lokuba phantse isiqingatha sezigulana ezinde ze-COVID ziye zaphazamiseka ekusebenzeni kwentliziyo ekuqaleni kophononongo, njengoko kubonisiwe yi-GLS.Nangona kunjalo, bonke abathathi-nxaxheba kuphononongo babonise iqhezu le-ejection eliqhelekileyo, elingumlinganiselo oqhelekileyo osetyenziselwa ukuvavanya ukucutha kwentliziyo kunye nobuchule bokuphumla ngexesha lokumpompa igazi.
UGqr. Leitman ugqibe kwelokuba iqhezu le-ejection lilodwa alikhathali ngokwaneleyo ukuchonga izigulana ezinde ze-COVID ezinokuthi zinciphise ukusebenza kwentliziyo.
Ukusetyenziswa kwonyango lwe-oxygen kunokuba neenzuzo ezinokubakho.
Ngokutsho kukaDkt Morgan, iziphumo zophando zibonisa indlela efanelekileyo kunye ne-hyperbaric oxygen therapy.
Nangona kunjalo, ucebisa isilumkiso, echaza ukuba unyango lwe-oxygen hyperbaric alulona unyango oluvunyiweyo jikelele kwaye lufuna uphando olongezelelweyo.Ukongezelela, kukho iinkxalabo malunga nokunyuka okunokwenzeka kwe-arrhythmias ngokusekelwe kuphando oluthile.
UGqr. Leitman kunye namaqabane akhe bagqibe kwelokuba unyango lwe-oxygen hyperbaric lunokuba luncedo kwizigulana ezine-COVID ende.Ucebisa ukuba uphando oluthe kratya luyimfuneko ukuchonga ukuba zeziphi izigulana ezinokuthi zixhamle kakhulu, kodwa kunokuba luncedo kuzo zonke izigulana ezinde ze-COVID ukuba ziye kuvavanyo loxinzelelo lwexesha elide kwaye zithathele ingqalelo unyango lwe-hyperbaric oxygen ukuba umsebenzi wabo wentliziyo uphazamisekile.
UDkt. Leitman naye uvakalisa ithemba lokuba izifundo ezongezelelweyo zinokubonelela ngeziphumo zexesha elide kunye nokuncedisa abaqeqeshi bezempilo ekunqumeni inani elifanelekileyo leeseshoni zonyango lwe-hyperbaric oxygen.
Ixesha lokuposa: Aug-05-2023