Uphononongo lwakutshanje luhlolisise imiphumo yonyango lwe-hyperbaric oxygen ekusebenzeni kwentliziyo yabantu abajongene ne-COVID ende, ebhekisa kwiingxaki ezahlukeneyo zempilo eziqhubekayo okanye eziphinda zibuye emva kokosulelwa yi-SARS-CoV-2.
Ezi ngxaki zinokubandakanya isigqi sentliziyo esingaqhelekanga kunye nomngcipheko okhulayo wokungasebenzi kakuhle kwentliziyo. Abaphandi bafumanise ukuba ukuphefumla ioksijini ecocekileyo nexineneyo kunokunceda ekuphuculeni ukushwabana kwentliziyo kwizigulana ezine-COVID ixesha elide.
Olu phononongo lukhokelwa nguNjingalwazi uMarina Leitman ovela kwiSackler School of Medicine kwiYunivesithi yaseTel Aviv kunye neShamir Medical Center e-Israel. Nangona iziphumo zavezwa kwingqungquthela eyayibanjwe ngoMeyi 2023 yi-European Society of Cardiology, azikaphononongwa ngontanga.
I-COVID ende kunye neenkxalabo zentliziyo
I-COVID ende, ekwabizwa ngokuba yi-post-COVID syndrome, ichaphazela malunga ne-10-20% yabantu abaye baba ne-COVID-19. Nangona uninzi lwabantu luchacha ngokupheleleyo kwi-virus, i-COVID ende inokuchongwa xa iimpawu ziqhubeka ubuncinane iinyanga ezintathu emva kokuqala kweempawu ze-COVID-19.
Iimpawu ze-COVID ende ziquka imiba eyahlukeneyo yezempilo, kubandakanya ukuphefumla kancinci, ubunzima bokuqonda (okubizwa ngokuba yi-brain fog), ukudakumba, kunye neengxaki ezininzi zentliziyo. Abantu abane-COVID ende basengozini enkulu yokufumana isifo sentliziyo, ukusilela kwentliziyo, kunye nezinye iimeko ezinxulumene noko.
Kwanabantu ababengenazo naziphi na iingxaki zentliziyo ngaphambili okanye ababenomngcipheko omkhulu wesifo sentliziyo baye bazibona ezi mpawu, njengoko kubonisiwe luphando olwenziwe ngo-2022.
Iindlela zophando
UGqr. Leitman kunye namaqabane akhe baqeshe izigulane ezingama-60 ezazineempawu ze-COVID-19 ezihlala ixesha elide, nokuba sele zikho iimeko ezingephi ukuya kweziphakathi, ezithathe ubuncinane iinyanga ezintathu. Eli qela laliquka abantu abalaliswe esibhedlele nabangengabo abalaliswe esibhedlele.
Ukuze benze uphando lwabo, abaphandi bahlukanise abathathi-nxaxheba baba ngamaqela amabini: elinye lifumana unyango lwe-hyperbaric oxygen (HBOT) kwaye elinye lifumana inkqubo yokulinganisa (i-sham). Umsebenzi wenziwa ngokungacwangciswanga, ngenani elilinganayo lezifundo kwiqela ngalinye. Kwiiveki ezisibhozo, umntu ngamnye wayefumana iiseshoni ezintlanu ngeveki.
Iqela le-HBOT lifumene i-oxygen eyi-100% kuxinzelelo lwe-atmospheres ezimbini kangangemizuzu engama-90, kunye nekhefu elifutshane rhoqo emva kwemizuzu engama-20. Kwelinye icala, iqela le-fake lifumene i-oxygen eyi-21% kuxinzelelo lwe-atmosphere enye ngexesha elifanayo kodwa ngaphandle kwekhefu.
Ukongeza, bonke abathathi-nxaxheba baye bavavanywa nge-echocardiography, uvavanyo lokuvavanya ukusebenza kwentliziyo, ngaphambi kweseshoni yokuqala ye-HBOT kunye neveki e-1 ukuya kwe-3 emva kweseshoni yokugqibela.
Ekuqaleni kolu phononongo, abathathi-nxaxheba abangama-29 kwabangama-60 babenexabiso eliphakathi le-global longitudinal strain (GLS) eliyi--17.8%. Phakathi kwabo, abali-16 babelwa kwiqela le-HBOT, ngelixa abali-13 abaseleyo babekwiqela elingelolokwenyani.
Iziphumo zophando
Emva kokufumana unyango, iqela lokungenelela liye lafumana ukunyuka okuphawulekayo kwi-avareji ye-GLS, yafikelela kwi--20.2%. Ngokufanayo, iqela le-fake nalo liye lafumana ukunyuka kwi-avareji ye-GLS, eyafikelela kwi--19.1%. Nangona kunjalo, kuphela umlinganiselo wangaphambili obonise umahluko omkhulu xa kuthelekiswa nomlinganiselo wokuqala ekuqaleni kophando.
UGqr. Leitman wenze uphononongo lokuba phantse isiqingatha sezigulana ezine-COVID ezinde zazingasebenzi kakuhle ekuqaleni kolu phando, njengoko kubonisiwe yi-GLS. Nangona kunjalo, bonke abathathi-nxaxheba kolu phando babonise iqhezu eliqhelekileyo lokukhupha igazi, eliyindlela eqhelekileyo yokulinganisa esetyenziselwa ukuvavanya amandla okuxinana kwentliziyo kunye nokuphumla ngexesha lokumpompa igazi.
UGqr. Leitman ugqibe kwelokuba iqhekeza lokukhupha igazi lodwa alinabo ubuthathaka ngokwaneleyo bokubona izigulana ze-COVID ezinde ezinokuba zingasebenzi kakuhle kwentliziyo.
Ukusetyenziswa konyango lweoksijini kunokuba neengenelo ezinokubakho.
Ngokutsho kukaGqr. Morgan, iziphumo zolu phononongo zibonisa ukuba kukho umkhwa omhle ngonyango lwe-hyperbaric oxygen.
Nangona kunjalo, ucebisa ukuba kuqatshelwe, esithi unyango lwe-hyperbaric oxygen alulonyango olwamkelweyo luluntu lonke kwaye lufuna uphando olongezelelweyo. Ukongeza, kukho iinkxalabo malunga nokwanda kwe-arrhythmias ngokusekelwe kuphando oluthile.
UGqr. Leitman kunye namaqabane akhe bagqibe kwelokuba unyango lwe-hyperbaric oxygen lunokuba luncedo kwizigulana ezine-COVID ende. Ucebisa ukuba uphando oluthe kratya luyimfuneko ukuchonga ukuba zeziphi izigulana eziza kuzuza kakhulu, kodwa kunokuba luncedo kuzo zonke izigulana ezine-COVID ende ukuba zivavanyelwe uxinzelelo lwe-longitudinal lwehlabathi kwaye zicinge ngonyango lwe-hyperbaric oxygen ukuba ukusebenza kwentliziyo yazo akulunganga.
UGqr. Leitman ukwavakalisa ithemba lokuba izifundo ezongezelelweyo zingabonelela ngeziphumo zexesha elide kwaye zincede iingcali zezempilo ekumiseleni inani elifanelekileyo leeseshoni zonyango lwe-oksijini ye-hyperbaric.
Ixesha lokuthumela: Agasti-05-2023