Unyango lwe-oksijini ye-Hyperbaric iphucula imisebenzi ye-neurocognitive yezigulane ze-post-stroke - uhlalutyo lokubuyela emva

Imvelaphi:

Uphononongo lwangaphambili lubonise ukuba unyango lwe-hyperbaric oxygen (HBOT) lunokuphucula imisebenzi yemoto kunye nememori yezigulane ze-post-stroke kwisigaba esingapheliyo.

Injongo:

Injongo yolu phononongo kukuvavanya imiphumo ye-HBOT kwimisebenzi yokuqonda ngokubanzi izigulane ezisemva kokuphazamiseka kwinqanaba elingapheliyo. Ubume, uhlobo kunye nendawo ye-stroke zaphandwa njengezilungisi ezinokwenzeka.

Iindlela:

Uhlalutyo lwe-retrospective lwenziwa kwizigulane eziphathwe nge-HBOT ye-stroke engapheliyo (> iinyanga ze-3) phakathi kwe-2008-2018. Abathathi-nxaxheba baphathwa kwi-multi-place hyperbaric chamber kunye ne-protocols elandelayo: i-40 kwiiseshoni ze-60 zemihla ngemihla, iintsuku ze-5 ngeveki, iseshoni nganye yayiquka i-90 min ye-100% i-oksijini kwi-2 ATA kunye ne-5 min air brakes yonke imizuzu ye-20. Uphuculo olubalulekileyo lweklinikhi (CSI) luchazwe njenge> 0.5 ukutenxa okusemgangathweni (SD).

Iziphumo:

Uphononongo lubandakanya izigulane ze-162 (i-75.3% yamadoda) kunye nobudala obuphakathi kwe-60.75±12.91. Kuzo, i-77 (47.53%) ine-cortical strokes, i-87 (53.7%) i-stroke ibekwe kwi-hemisphere yasekhohlo kwaye i-121 yafumana i-ischemic strokes (74.6%).
I-HBOT yenze ukwanda okubonakalayo kuyo yonke imimandla yokusebenza kwengqondo (p <0.05), kunye ne-86% yamaxhoba e-stroke afezekisa i-CSI. Kwakungekho nantlukwano ebalulekileyo emva kwe-HBOT ye-cortical stroke xa kuthelekiswa ne-sub-cortical strokes (p> 0.05). Imivimbo ye-Hemorrhagic yayinophuculo oluphezulu kakhulu kwisantya sokulungiswa kolwazi emva kwe-HBOT (p <0.05). Imivimbo ye-hemisphere yekhohlo ibe nokunyuka okuphezulu kwi-motor domain (p <0.05). Kuzo zonke imimandla yokuqonda, umsebenzi wokuqonda isiseko wawuyi-predictor ebalulekileyo ye-CSI (p <0.05), ngelixa uhlobo lwe-stroke, indawo kunye necala lalingabalulekanga.

Izigqibo:

I-HBOT yenza uphuculo olubalulekileyo kuzo zonke iindawo zengqondo nakwinqanaba elingapheliyo. Ukukhethwa kwezigulane ze-post-stroke ze-HBOT kufuneka zisekelwe kuhlalutyo olusebenzayo kunye namanqaku okuqonda okusisiseko kunohlobo lwe-stroke, indawo okanye icala le-lesion.