Unyango lwe-oksijini ye-hyperbaric luphucula imisebenzi ye-neurocognitive yezigulane emva kwe-stroke - uhlalutyo olujonga emva

Imvelaphi:

Izifundo zangaphambili zibonise ukuba unyango lwe-hyperbaric oxygen therapy (HBOT) lunokuphucula imisebenzi yokunyakaza komzimba kunye nenkumbulo yezigulane ezisandul’ ukubetheka kwisigaba esingapheliyo.

Injongo:

Injongo yolu phononongo kukuvavanya imiphumo ye-HBOT kwimisebenzi yokuqonda ngokubanzi yezigulane ezisandula ukubetheka kwisigaba esingapheliyo. Uhlobo, uhlobo kunye nendawo yebetheko ziphandwe njengeziguquli ezinokwenzeka.

Iindlela:

Uhlalutyo olujonga emva lwenziwe kwizigulana ezanyangwa nge-HBOT ngenxa yestroke esingapheliyo (>iinyanga ezi-3) phakathi kowama-2008-2018. Abathathi-nxaxheba banyangwa kwigumbi elineendawo ezininzi ze-hyperbaric ngeenkqubo ezilandelayo: iiseshoni zemihla ngemihla ezingama-40 ukuya kuma-60, iintsuku ezi-5 ngeveki, iseshoni nganye yayiquka imizuzu engama-90 ye-oxygen eyi-100% kwi-2 ATA kunye neebhuleki zomoya zemizuzu emi-5 rhoqo emva kwemizuzu engama-20. Uphuculo olubalulekileyo lwezonyango (CSI) luchazwe njenge-> 0.5 standard deviation (SD).

Iziphumo:

Olu phononongo luquke izigulane ezili-162 (amadoda angama-75.3%) kunye nobudala obuphakathi obuyi-60.75±12.91. Kubo, abangama-77(47.53%) babene-cortical strokes, abangama-87(53.7%) babekwi-left hemisphere kwaye abali-121 babene-ischemic strokes (74.6%).
I-HBOT ibangele ukwanda okukhulu kuzo zonke iindawo zomsebenzi wokuqonda (p < 0.05), apho ama-86% amaxhoba estroke efikelela kwi-CSI. Akukho mahluko abalulekileyo emva kwe-HBOT kwi-cortical strokes xa kuthelekiswa ne-sub-cortical strokes (p > 0.05). I-hemorrhagic strokes ibe nokuphucuka okuphezulu kakhulu kwisantya sokucubungula ulwazi emva kwe-HBOT (p < 0.05). I-left hemisphere strokes ibe nokwanda okuphezulu kwi-motor domain (p < 0.05). Kuzo zonke iindawo zokuqonda, umsebenzi wesiseko wokuqonda wawusisibikezelo esibalulekileyo se-CSI (p < 0.05), ngelixa uhlobo lwestroke, indawo kunye necala zazingezizo izibikezelo ezibalulekileyo.

Izigqibo:

I-HBOT ibangela uphuculo olukhulu kuzo zonke iinkalo zengqondo kwanakwinqanaba lokugqibela lesifo esinganyangekiyo. Ukukhethwa kwezigulane emva kwesifo sohlangothi ze-HBOT kufuneka kusekelwe kuhlalutyo olusebenzayo kunye namanqaku okuqala okuqonda kunohlobo lwesifo sohlangothi, indawo okanye icala lesilonda.