Unyango lweNhlungu ezingapheliyo: Isayensi ebangela unyango lwe-oksijini ye-Hyperbaric

Iindlela Ezisemva Konyango Lwe-Oxygen Ye-Hyperbaric Yokunceda Ubuhlungu

1. Ukuphuculwa kweemeko ezibangela iHypoxia

Iimeko ezininzi ezibuhlungu zinxulunyaniswa nokungabikho koxinzelelo lwe-tissue kunye ne-ischemia. Kwimeko-bume ene-hyperbaric, umxholo we-oksijini egazini uyanda kakhulu. Ngokwesiqhelo, igazi le-arterial linomxholo we-oksijini omalunga ne-20 ml/dl; nangona kunjalo, oku kunokunyuka ngokukhawuleza kwindawo ene-hyperbaric. Amanqanaba aphezulu e-oksijini anokusasazeka kwiithishu ze-ischemic kunye ne-hypoxic, okwandisa ukunikezelwa kwe-oksijini kwaye kunciphise ukuqokelelwa kweemveliso ze-asidi ze-metabolic ezibangela intlungu.

Izicubu zemithambo-luvo zinobuthathaka kakhulu kwi-hypoxia. Unyango lwe-oksijini e-hyperbaric lunyusa uxinzelelo oluncinci lwe-oksijini kwizicubu zemithambo-luvo, luphucula imeko ye-hypoxia kwi-nerve fibers kunye ukunceda ekulungiseni nasekubuyiseleni ukusebenza kwemithambo-luvo eyonakeleyo, njengakwizithintelo zemithambo-luvo esecaleni, apho inokukhawulezisa ukulungiswa kwe-myelin sheath kwaye inciphise iintlungu ezinxulumene nomonakalo wemithambo-luvo.

2. Ukunciphisa impendulo yokuvuvukala

Unyango lwe-hyperbaric oxygen lunokunceda ekulawuleni amanqanaba ezinto ezibangela ukudumba ezifana ne-interleukin-1 kunye ne-tumor necrosis factor-alpha emzimbeni. Ukunciphisa iimpawu zokudumba kunciphisa ukukhuthazwa kwezicubu ezijikelezileyo kwaye emva koko kunciphisa iintlungu. Ngaphezu koko, i-hyperbaric oxygen inciphisa imithambo yegazi kwaye inciphise ukuhamba kwegazi kwindawo, inciphise ukungena kwe-capillary kwaye ngaloo ndlela inciphise ukudumba kwezicubu. Umzekelo, kwiimeko zokwenzakala kwezicubu ezithambileyo, ukunciphisa ukudumba kunokunciphisa uxinzelelo kwiziphelo zemithambo-luvo ezingqongileyo, kunciphise iintlungu ngakumbi.

3. Ulawulo lomsebenzi weNkqubo yeNervous

Unyango lwe-hyperbaric oxygen lunokulawula ukuvuseleleka kwenkqubo yemithambo-luvo enovelwano, luphucule ithoni yemithambo-luvo kwaye lunciphise iintlungu. Ukongeza, lunokukhuthaza ukukhululwa kwee-neurotransmitters ezifana nee-endorphins, ezineempawu ezinamandla zokuthomalalisa iintlungu, nto leyo enegalelo ekunciphiseni ukuqonda iintlungu.

 

Ukusetyenziswa kwe-Hyperbaric Oxygen Therapy kwi-Pain Management

1. Unyango lweI-Complex Regional Pain Syndrome(CRPS)

I-CRPS ibonakaliswa ziintlungu eziqatha, ukudumba, kunye notshintsho lolusu njengemeko engapheliyo yomzimba. I-hypoxia kunye ne-acidosis enxulunyaniswa ne-CRPS ziyandisa iintlungu kwaye zinciphise ukunyamezela iintlungu. Unyango lwe-oksijini e-hyperbaric lubangela indawo ene-oksijini ephezulu enokuthi inciphise imithambo yegazi, inciphise ukudumba, kwaye yonyuse uxinzelelo lwe-oksijini yezicubu. Ngaphezu koko, ivuselela umsebenzi we-osteoblasts ecinezelweyo, inciphise ukwakheka kwezicubu ezine-fibrous.

2. Ulawulo lweI-Fibromyalgia 

I-Fibromyalgia yimeko engachazwanga eyaziwa ngokuba neentlungu ezixhaphakileyo kunye nokungonwabi okukhulu. Izifundo zibonise ukuba i-hypoxia yendawo inegalelo kutshintsho oluwohlokayo kwimisipha yabantu abane-fibromyalgia.

yonyusa uxinano lweoksijini kwizicwili ngaphezulu kakhulu kwamanqanaba e-physiological, ngaloo ndlela iphula umjikelo we-hypoxic-pain kwaye inike isiqabu kwiintlungu.

3. Unyango lwe-Postherpetic Neuralgia

I-postherpetic neuralgia ibandakanya intlungu kunye/okanye ukurhawuzelelwa emva kwe-shingles. Uphando lubonisa ukuba unyango lwe-hyperbaric oxygen lunciphisa iintlungu kunye namanqaku okudakumba kwizigulana ezinengxaki yesi sifo.

4. Uncedo lweIntlungu ye-Ischemic kwi-Extremities esezantsi 

Isifo sokuvaleka kwemithambo yegazi ngenxa ye-atherosclerotic, i-thrombosis, kunye neemeko ezahlukeneyo zemithambo yegazi zihlala zikhokelela kwiintlungu ze-ischemic kwimilenze. Unyango lwe-oksijini ene-hyperbaric lunokunciphisa iintlungu ze-ischemic ngokunciphisa i-hypoxia kunye nokudumba, kunye nokunciphisa ukuqokelelwa kwezinto ezibangela iintlungu ngelixa kuphucula i-endorphin-receptor affinity.

5. Ukunciphisa i-Trigeminal Neuralgia

Unyango lwe-hyperbaric oxygen luye lwabonisa ukuba lunciphisa amanqanaba entlungu kwizigulana ezine-trigeminal neuralgia kwaye lunciphisa isidingo se-analgesics yomlomo.

 

Isiphelo

Unyango lwe-oksijini egqithisileyo lubonakala njengonyango olusebenzayo lweentlungu ezingapheliyo, ingakumbi xa unyango oluqhelekileyo lungaphumeleli. Indlela yalo eneenkcukacha ezininzi yokuphucula ukunikezelwa kweoksijini, ukunciphisa ukudumba, kunye nokulawula imisebenzi yemithambo-luvo yenza kube lukhetho olunomtsalane kwizigulana ezifuna ukukhululeka kwiintlungu. Ukuba unesifo seentlungu ezingapheliyo, cinga ngokuxoxa ngonyango lwe-oksijini egqithisileyo njengendlela entsha yonyango.