Isiphumo sokubulala iintsholongwane sonyango lwe-oksijini ye-hyperbaric kwizilonda zokutsha

Intshayelelo

Ukulimala kokutsha kudla ngokufunyanwa kwiimeko ezingxamisekileyo kwaye kudla ngokuba yindawo yokungena kwezifo ezibangelwa ziintsholongwane. Ukulimala kokutsha okungaphezulu kwama-450,000 kwenzeka minyaka le nto kubangele ukufa okuphantse kube ngama-3,400 eMelika. Ukuxhaphaka kokulimala kokutsha e-Indonesia yi-0.7% ngo-2013. Ngaphezulu kwesiqingatha sale mithi Ngokwezifundo ezininzi zokusetyenziswa kwezigulana zanyangwa usulelo lweebhaktheriya, ezinye zazo ezazingamelani nee-antibiotics ezithile.unyango lwe-hyperbaric oxygen(HBOT) yokunyanga ukutsha ineziphumo ezininzi ezilungileyo kuquka ukulawula usulelo lweentsholongwane, kunye nokukhawulezisa inkqubo yokuphiliswa kwamanxeba. Ke ngoko, olu phononongo lujolise ekubonakaliseni ukusebenza kakuhle kwe-HBOT ekuthinteleni ukukhula kweentsholongwane.

Iindlela

Olu luphando lovavanyo kwimivundla olusebenzisa uyilo lweqela lolawulo emva kovavanyo. Imivundla engama-38 yatshiswa ngokwenqanaba lesibini kummandla wamagxa ngepleyiti yesinyithi yesinyithi ebifudunyezwe ngaphambili imizuzu emi-3. Iintsholongwane zathathwa kwiintsuku zesi-5 neze-10 emva kokuvezwa kukutsha. Iisampulu zahlulwe zangamaqela amabini, i-HBOT kunye nolawulo. Uhlalutyo lwezibalo lwenziwe kusetyenziswa indlela kaMann-Whitney U.

Iziphumo

Iintsholongwane ezinegram-negative beziyeyona ntsholongwane ixhaphakileyo efumaneka kuzo zombini ezi qela. I-Citrobacter freundi yayiyeyona ntsholongwane inegram-negative ixhaphakileyo (34%) efunyenwe kwiziphumo zokukhula kwamaqela omabini.

Ngokungafaniyo neqela lolawulo, akukho kukhula kwebhaktiriya kufunyenweyo kwiziphumo zenkcubeko yeqela le-HBOT, (0%) vs (58%). Ukuncipha okukhulu kokukhula kwebhaktiriya kubonwe kwiqela le-HBOT (69%) xa kuthelekiswa neqela lolawulo (5%). Amanqanaba ebhaktiriya ami kwimivundla emi-6 (31%) kwiqela le-HBOT kunye nemivundla esi-7 (37%) kwiqela lolawulo. Lilonke, bekukho ukukhula okuncinci kakhulu kwebhaktiriya kwiqela lonyango lwe-HBOT xa kuthelekiswa neqela lolawulo (p < 0.001).

Isiphelo

Ukunikwa kwe-HBOT kunokunciphisa kakhulu ukukhula kweebhaktheriya kwizilonda zokutsha.