Umphumo we-bactericidal we-hyperbaric oxygen therapy kukulimala kokutshisa

Intshayelelo

Ukwenzakala okutshisayo kuhlangana rhoqo kwiimeko ezingxamisekileyo kwaye kaninzi kuba lizibuko lokungena kwi-pathogens.Ngaphezulu kwama-450,000 amanxeba okutsha ayenzeka ngonyaka abangela ukufa kwabantu abaphantse babe ngama-3,400 eUnited States.Ukuxhaphaka kokulimala kokutshisa e-Indonesia yi-0.7% kwi-2013. Ngaphezu kwesiqingatha salezi Ngokwezifundo ezininzi malunga nokusetyenziswa kwezigulane zaphathwa ngenxa yezifo zebhaktheriya, ezinye zazo ezazichasene ne-antibiotics ethile.Ukusebenzisaunyango lwe-oxygen hyperbaric(HBOT) ukunyanga ukutsha kuneziphumo ezininzi ezintle ezibandakanya ukulawula usulelo lwebhaktiriya, kunye nokukhawulezisa inkqubo yokuphilisa inxeba.Ke ngoko, olu phononongo lujolise ekubonakaliseni ukusebenza kwe-HBOT ekunqandeni ukukhula kwebhaktheriya.

Iindlela

Olu luphando lophando kwimivundla kusetyenziswa uyilo lweqela lolawulo lwasemva kovavanyo.Imivundla ye-38 inikwe ukutshiswa kwe-second-degree kwingingqi yegxalaba kunye nentsimbi yentsimbi esele ishushu ngaphambili kwi-3 min.Iinkcubeko zebhaktheriya zithathwe ngeentsuku ze-5 kunye ne-10 emva kokuvezwa kokutshisa.Iisampuli zahlulahlulwe ngamaqela amabini, i-HBOT kunye nolawulo.Uhlalutyo lwamanani lwenziwa kusetyenziswa indlela kaMann-Whitney U.

Iziphumo

Iibhaktheriya zegram-negative zezona zifunyenwe rhoqo kumaqela omabini.I-Citrobacter freundi yeyona bhaktheriya ixhaphakileyo ye-Gram-negative (34%) efunyenwe kwiziphumo zenkcubeko zamaqela omabini.

Ngokuchasene neqela lokulawula, akukho kukhula kwebhaktheriya efunyenwe kwiziphumo zenkcubeko yeqela le-HBOT, (0%) vs (58%).Ukunciphisa okuphawulekayo kokukhula kwebhaktheriya kwabonwa kwiqela le-HBOT (69%) xa kuthelekiswa neqela lokulawula (5%).Amanqanaba ebhaktheriya amile kwimivundla eyi-6 (31%) kwiqela le-HBOT kunye nemivundla eyi-7 (37%) kwiqela lolawulo.Ngokubanzi, kwakukho ukukhula okuncinci kwebhaktheriya kwiqela lonyango lwe-HBOT xa kuthelekiswa neqela lokulawula (p <0.001).

Ukuqukumbela

Ulawulo lwe-HBOT lunokunciphisa kakhulu ukukhula kwebhaktheriya kukulimala kokutshisa.